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SS-31 Review | SS-31 Benefits And Effects

SS-31 Review
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In this SS-31 review we look at its potential in research and how it works. SS-31 is also known as Bendavia. It is a mitochondrial-targeted peptide that is effective in various health conditions. Studies show that it can improve mitochondrial function, which is crucial in producing energy (ATP) within cells and maintaining cellular health. SS-31 targets the inner mitochondrial membrane, which scavenges reactive oxygen species (ROS) and protects mitochondrial DNA and proteins from oxidative damage. Research suggests that SS-31 may benefit a range of conditions, as you mentioned, including neurodegenerative diseases like Alzheimer’s and Parkinson’s, cardiovascular diseases, diabetes, kidney diseases, and more. It can reduce oxidative stress and inflammation by targeting mitochondrial dysfunction, which is thought to underlie these potential therapeutic effects.

What Is The Mechanism Of Action Of SS31?

Recent findings propose that SS-31 effectively curbs cardiolipin (CL) peroxidation through a dual-pronged approach. Notably, it demonstrates prowess in diminishing mitochondrial ROS by efficiently scavenging H2O2. Furthermore, it showcases the capability to impede cyt c peroxidase activity directly. While promising, further investigations are imperative to validate its direct efficacy in curbing CL peroxidation in vivo. Stay tuned for unfolding insights.

What Is SS 31 Peptide?

SS-31, classified as a synthetic peptide, is a remarkable innovation in the realm of mitochondrial enhancement. Presently, it stands under the spotlight of clinical trials, showcasing its potential in heart failure, primary mitochondrial myopathy, and diverse mitochondrial disorders. SS-31’s prowess lies in its capacity to elevate mitochondrial function, a key attribute driving its exploration for therapeutic applications.

Extensive research reveals that SS-31 operates by efficiently counteracting oxidative stress, promoting electron transport chain efficiency, and protecting against mitochondrial membrane permeabilization. These multidimensional mechanisms illuminate their promising role in mitigating mitochondrial dysfunction-related ailments, paving the way for potential breakthroughs in medical treatment.[1]

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What Are SS-31 Peptide Benefits?

SS-31 Peptide Benefits: Beyond Neuroprotection the benefits of SS-31 peptide extend far beyond neuroprotection, encompassing notable cardioprotective effects across various disease models. Through robust studies, SS-31 has the potential as a potent cardioprotective agent.[2]

  1. Cardiac Ischemia-Reperfusion Injury: SS-31 emerges as a remarkable contender in cardiac health by exhibiting significant cardioprotective effects in cases of ischemia-reperfusion injury. Studies underscore its ability to mitigate the damaging consequences of this process, potentially offering new avenues for intervention and recovery.
  2. Reperfusion Arrhythmia: SS-31’s impact is not only on injury prevention alone. It also promises to mitigate reperfusion arrhythmias, a condition marked by irregular heart rhythms following ischemia. This dual-action potential highlights SS-31’s versatility in addressing multifaceted cardiovascular challenges.
  3. Myocardial Infarction Models: The peptide’s prowess extends even further, with encouraging results in myocardial infarction models. Here, SS-31 demonstrates its potential to minimize the aftermath of heart attacks, potentially leading to improved post-infarction recovery and reduced damage.
  4. Cardiac Hypertrophy and Heart Failure: Research uncovers SS-31’s ability to shield against cardiac hypertrophy, a condition characterized by abnormal heart enlargement. Furthermore, it showcases promise in safeguarding against heart failure, a significant medical concern. These findings hint at SS-31’s potential to address and mitigate the progression of these cardiovascular conditions.
  5. Mitochondrial Function Enhancement: Beyond its cardioprotective role, SS-31 enhances mitochondrial function. By counteracting oxidative stress and bolstering the efficiency of the electron transport chain, SS-31 contributes to the maintenance of cellular energy production and overall health.[3]

In summary, the SS-31 peptide is a multifaceted asset in medical research. It has proven neuroprotection [4] and an array of cardioprotective effects, including ischemia-reperfusion injuries, arrhythmias, myocardial infarctions, hypertrophy, and heart failure. Ultimately, SS-31 shows potential for revolutionizing treatment approaches in both neurological and cardiovascular domains.[5]

SS-31 Review
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SS-31’s Review And The Impact On Alzheimer’s Disease and Beyond

SS-31, a research peptide renowned for its adeptness in bolstering mitochondrial function and catalyzing ATP synthesis – the crux of cellular energy production – is a promise in medical research. While its effects are far-reaching, one realm where SS-31’s potential shines exceptionally well is Alzheimer’s disease.[6]

The saga of SS-31’s benefits begins with its ability to thwart the onslaught of inflammatory cytokines. These molecular actors, orchestrators of oxidative stress and inflammation, are central to the pathogenesis of many diseases. Extensive studies reveal that SS-31 exerts a remarkable influence, effectively curbing the surge of these cytokines. Thus reducing inflammation and potentially alleviating oxidative stress, paving a path for lessening the consequences of various inflammatory conditions.

Amidst these achievements, SS-31 emerges as a knight in shining armor against neurodegenerative disorders. Alzheimer’s disease, a debilitating condition characterized by cognitive decline and neuronal damage, comes into the spotlight. The cascade of events in Alzheimer’s, including oxidative stress and inflammation, finds a formidable opponent in SS-31. Its ability to enhance mitochondrial function and mitigate inflammation positions it as a potential shield against the ravages of Alzheimer’s.

The reach of SS-31 extends beyond neurology. Conditions as diverse as Parkinson’s, heart disease, diabetes, and kidney disease are within its sphere of influence. The compound’s multifaceted approach, targeting cellular energy production, oxidative stress, and inflammation, paints a promising picture for various medical challenges.

With SS-31, it is a journey towards improving well-being and cellular health. The alliance of scientific exploration and SS-31’s remarkable properties holds the promise of unlocking new results in the battle against Alzheimer’s and a multitude of other disorders. Embrace the possibilities and step into a future empowered by SS-31’s potential.

Update: SS-31 Review For Weight Loss

The research peptide SS-31 emerges as a fascinating contender for effective weight loss solutions. With a focus on exploring the benefits of SS-31 in managing body weight, recent studies have unveiled intriguing findings that hold promise for those seeking weight management strategies.

One study delved into the effects of SS-31 administration, utilizing 2 mg/kg, on mice bearing the C26 tumor. The results revealed a noteworthy outcome: SS-31 exhibited the ability to counteract body weight loss in these mice partially. Impressively, the treated group experienced an 11% increase in body weight compared to untreated C26 mice.

However, it’s important to note that the benefits of SS-31 appeared to be specific to body weight, as the peptide did not correct muscle wasting in the same group of mice: Ultimatley, the complexity of the relationship between SS-31 and various aspects of physiological response.

Interestingly, when tested on C26 OXFU mice, SS-31 did not prevent body and muscle weight loss. These divergent results highlight the intricacies involved in the interaction between SS-31 and physiological contexts.

The exact mechanisms behind SS-31’s influence on body weight are yet to be fully recognised. But, they offer a tantalizing glimpse into the potential of SS-31 as a contributor to weight management strategies. As ongoing research continues to unveil the complexities of SS-31’s effects, there’s a growing anticipation for the broader insights it may bring to weight loss and beyond.

For those intrigued by the intersection of SS-31 and weight loss, these findings underscore the importance of staying attuned to emerging research. As science advances, SS-31 may be essential to unlocking novel approaches to achieving healthier body weights.

[Link to Original Research Study]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923037/#:~:text=SS%2D31%20administration%20(2%20mg, Figure%201a%E2%80%93c).

Latest Updates : SS-31 Research Peptide’s Potential In Diabetes

In the realm of diabetes research, the research peptide SS-31 is emerging as a beacon of hope, offering potential benefits that extend beyond conventional treatments. Recent studies have ventured into uncharted territory, revealing intriguing insights into SS-31’s impact on individuals with Type 2 Diabetes (T2D).

Among its diverse effects, SS-31 demonstrates a fascinating ability to influence leukocyte behavior in T2D patients. Specifically, it manages to decrease rolling flux and leukocyte adhesion while simultaneously boosting rolling velocity. These alterations at the cellular level hint at SS-31’s profound influence on the intricate processes within the bodies of T2D patients.

One of the critical factors underpinning these effects is SS-31’s modulation of oxidative stress and autophagy. By exerting its influence at this fundamental level, SS-31 showcases its potential to bring about positive changes in T2D patients, potentially contributing to a more balanced and harmonious cellular environment.

Furthermore, SS-31’s reach extends to tackling endoplasmic reticulum (ER) stress. This phenomenon, closely linked to cellular dysfunction and diabetes, finds an adversary in SS-31. The peptide’s ability to facilitate ER stress holds promise for potentially alleviating some of the complications associated with T2D.

As research into SS-31’s effects on diabetes continues to evolve, these findings pave the way for a new understanding of how this peptide may revolutionize diabetes management. With its multifaceted approach targeting oxidative stress, autophagy, and ER stress, SS-31 is a potential ally in the battle against the complexities of Type 2 Diabetes.

For those navigating the challenges of diabetes, SS-31’s potential offers a glimmer of hope. As we delve deeper into the complexities of its effects, SS-31 promises to open new doors to improved well-being and diabetes management strategies. Stay connected to the evolving landscape of scientific inquiry and consider the possibilities SS-31 could hold on your journey to a healthier future.[8]

Review Of SS-31 Research Peptide For Enhanced Cellular Health

The benefits of SS-31 are multifaceted. It infuses mitochondria with renewed energy, bolstering their functionality. It also plays the role of a harmonizer, adeptly balancing the scales between free radicals and antioxidants. By doing so, SS-31 mitigates the looming threat of oxidative stress, a pivotal contributor to various health complications.

As its impact resonates within the cellular realm, SS-31 holds the promise of safeguarding against many chronic afflictions. Among these, the potential ripple effects of SS-31 span across:

  1. Cancer: By addressing mitochondrial dysfunction and oxidative stress, SS-31 may play a role in curbing the cellular conditions conducive to cancer development.
  2. Inflammation: The interplay between oxidative stress and inflammation finds an equilibrium through SS-31’s harmonizing effects, potentially reducing the likelihood of inflammatory responses.
  3. Neurological Disorders: Mitochondrial health is crucial for neurological well-being. SS-31’s ability to enhance mitochondrial function could hold implications for neuroprotection.
  4. Diabetes: Addressing the root causes of Type 2 Diabetes, SS-31’s energy-boosting and balancing attributes have the potential to alleviate hyperglycemic stress and insulin resistance.

In essence, SS-31 introduces a promising avenue for pursuing enhanced cellular health. It unveils a potential pathway toward a healthier, more resilient future by fortifying mitochondria, balancing oxidative stress, and thwarting the emergence of chronic conditions. As research reveals the layers of SS-31’s impact, its significance in medical advancements becomes increasingly evident.[9]

SS-31 Review: Buy Peptide Sciences SS-31 For Research Use Only

Disclaimer

We bring this information to you for general knowledge purposes about research products and their uses. The  medical problems discussed are for information use only. The products available on this website are for education and research use only. They are not for human consumption or use on animals. We supply Peptide Sciences products for laboratory research and not for any diagnostic, therapeutic or in vivo use on animals or the human body. Every product we sell is manufactured according to the research industry guidelines. This post may contain affiliate links but at no extra cost to you the buyer. Plus, external links for further resources. See our disclaimer here. For more read about us and our privacy policy.

REFERENCES

[1] SS-31, a Mitochondria-Targeting Peptide, Ameliorates Kidney Disease

[2] Mitochondria-Targeted Antioxidant SS-31 is a Potential Novel Ophthalmic Medication for Neuroprotection in Glaucoma

[3] Mitochondrial protein interaction landscape of SS-31

[4] SS-31 (also known as Elamipretide®, Bendavia®, and MTP-131)

[5] SS-31 Peptide Reverses the Mitochondrial Fragmentation Present in Fibroblasts From Patients With DCMA, a Mitochondrial Cardiomyopathy

[6] Mitochondrial dysfunction and beneficial effects of mitochondria-targeted small peptide SS-31 in Diabetes Mellitus and Alzheimer’s disease

[7] The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes

[8] The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes

[9] SS-31 research peptide

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Buy SS-31  If you are looking to buy SS-31 peptide for study use only, Peptide Sciences is a reputable company worth considering. Peptide Sciences is known for its commitment to providing high-quality peptides for research purposes. They prioritize stringent quality control measures, ensuring the purity, authenticity, and potency of their products. With a solid reputation within the scientific community, Peptide Sciences sources their peptides from reputable manufacturers and follows strict manufacturing standards. They also employ rigorous testing procedures to ensure the integrity of their peptides.[1]

Furthermore, Peptide Sciences offers excellent customer service, knowledgeable support, and secure packaging to ensure a smooth and reliable purchasing experience. When it comes to buying SS-31 peptide for study purposes, you can trust Peptide Sciences to deliver a reliable and high-quality product

What Is SS-31 Peptide?

SS-31 specifically targets the mitochondria, which are the energy-producing powerhouses of our cells. It is designed to penetrate cell membranes and accumulate in the mitochondria, where it aims to protect and improve their function.[2]

Research on SS-31 suggests that it has potential benefits in various areas, including cardiovascular health, neurodegenerative diseases, and age-related mitochondrial dysfunction. It has been investigated for its ability to reduce oxidative stress, inflammation, and apoptosis (programmed cell death), while promoting mitochondrial stability and energy production.

Additionally, SS-31 has shown promise in preclinical studies for its potential to protect the heart from damage during ischemic events (reduced blood flow) and improve cardiac function. It may also have neuroprotective effects, potentially benefiting conditions such as Alzheimer’s disease and Parkinson’s disease.

What Does SS-31 Do?

SS-31, also known as Bendavia or MTP-131, is a research peptide that specifically targets and interacts with mitochondria, the energy-producing structures within our cells. Here’s a breakdown of what SS-31 is believed to do based on current research:

Mitochondrial Protection

SS-31 aims to protect mitochondria from damage and dysfunction. Mitochondria play a crucial role in cellular energy production and various other cellular processes, and SS-31 is designed to improve their function and stability.[3]

Reducing Oxidative Stress

SS-31 is known for its potential to reduce oxidative stress within mitochondria. Oxidative stress occurs when there is an imbalance between the production of harmful reactive oxygen species (ROS) and the body’s ability to neutralize them. By reducing oxidative stress, SS-31 may help mitigate cellular damage caused by ROS.

Anti-inflammatory Effects

Research suggests that SS-31 exhibits anti-inflammatory properties. Inflammation is a natural response of the immune system, but excessive or chronic inflammation can be harmful. SS-31 may help modulate inflammatory processes, potentially reducing inflammation and its negative effects.

Apoptosis Regulation

SS-31 has been studied for its ability to modulate apoptosis, which is programmed cell death. In certain situations, uncontrolled or excessive apoptosis can contribute to tissue damage or dysfunction. SS-31 may help regulate this process, promoting cellular survival when appropriate.

Cardiovascular Benefits

SS-31 has shown promise in preclinical studies for its potential cardiovascular benefits. It may protect the heart from damage during ischemic events (reduced blood flow) and improve cardiac function. These effects may be attributed to the peptide’s ability to enhance mitochondrial function and reduce oxidative stress in cardiac cells.

What Are The Benefits Of SS-31 Peptide?

SS-31 peptide, also known as Bendavia or MTP-131, has been studied for its potential benefits in various areas. While research is still ongoing, here are some of the potential benefits associated with SS-31 based on current scientific knowledge:

Mitochondrial Protection

SS-31 targets mitochondria, the energy-producing organelles in cells, and aims to protect them from damage and dysfunction. By improving mitochondrial function and stability, SS-31 may contribute to overall cellular health and energy production.

Reducing Oxidative Stress

SS-31 has shown potential in reducing oxidative stress within mitochondria. Oxidative stress occurs when there is an imbalance between the production of harmful reactive oxygen species (ROS) and the body’s ability to neutralize them. By reducing oxidative stress, SS-31 may help mitigate cellular damage caused by ROS.

Anti-inflammatory Effects

Research suggests that SS-31 exhibits anti-inflammatory properties. It may help modulate inflammatory processes, potentially reducing inflammation and its associated negative effects. This could be beneficial in conditions characterized by excessive or chronic inflammation.

Cardioprotective Effects

SS-31 has been investigated for its potential to protect the heart from damage during ischemic events (reduced blood flow) and improve cardiac function. By targeting and protecting mitochondria within cardiac cells, SS-31 may help maintain or restore cardiovascular health.

Neuroprotective Potential

SS-31 shows promise as a neuroprotective agent. It may have the ability to protect neurons from damage, which could be relevant in neurodegenerative diseases such as Alzheimer’s and Parkinson’s. By targeting mitochondria within brain cells, SS-31 aims to support their function and counteract detrimental processes.

It’s important to note that while these potential benefits are based on scientific research, further studies are needed to fully understand the effects, and long-term safety profile of SS-31.[4]

What Is The Mechanism Of SS-31?

The mechanism of SS-31, also known as Bendavia or MTP-131, is primarily related to its interaction with mitochondria, the energy-producing organelles within our cells. Here’s an overview of the key mechanisms associated with SS-31:

Mitochondrial Targeting

SS-31 is designed to selectively accumulate within the mitochondria of cells. It can easily penetrate cell membranes and reach the mitochondria due to its unique chemical properties. Once inside the mitochondria, SS-31 exerts its effects on mitochondrial function.

Reduction of Oxidative Stress

SS-31 aims to reduce oxidative stress within mitochondria. Mitochondria are susceptible to oxidative damage caused by reactive oxygen species (ROS). SS-31 has been shown to scavenge and neutralize ROS, helping to maintain the delicate balance of cellular redox reactions and minimize oxidative stress.

Stabilization of Mitochondrial Membrane Potential

SS-31 interacts with the inner membrane of mitochondria and helps stabilize the mitochondrial membrane potential. This potential is essential for the efficient generation of cellular energy (ATP) by the mitochondria. By maintaining the membrane potential, SS-31 supports optimal mitochondrial function and energy production.

Modulation of Apoptosis

SS-31 has been found to regulate apoptosis, which is programmed cell death. Excessive or uncontrolled apoptosis can lead to tissue damage and dysfunction. SS-31’s interaction with mitochondria may help modulate apoptotic processes, promoting cell survival when appropriate and preventing unnecessary cell death.

Research suggests that SS-31 exhibits anti-inflammatory properties. It can help modulate inflammatory signaling pathways and reduce the production of pro-inflammatory molecules. By mitigating excessive inflammation, SS-31 may contribute to tissue protection and improved cellular function.[5]

Buy SS-31 50mgThe exact details of SS-31’s mechanisms are still being studied, and further research is needed to fully elucidate its actions. However, the peptide’s unique ability to target and protect mitochondria makes it a promising candidate for various applications.

Please note that the information provided here is based on current scientific knowledge, and any specific application of SS-31. It is not for human consumption.

When considering the purchase of SS-31 peptide, it is crucial to ensure that you buy from a reliable and reputable peptide company. Reliable companies prioritize quality, purity, and customer satisfaction.

Here’s a paragraph highlighting the benefits of buying from a trusted peptide company:

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Look no further than a reputable and reliable peptide company Peptide Sciences. A trusted peptide supplier, you can have peace of mind knowing that you are obtaining a high-quality product. Peptide Sciences prioritize stringent quality control measures, ensuring the purity, potency, and authenticity of their peptides. They are a reputable manufacturer, that adhere to strict manufacturing standards, and employ rigorous testing[6] procedures.

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By purchasing from a reliable peptide company, you can trust that you are getting a genuine SS-31 peptide that meets the highest industry standards. Additionally, reputable companies often provide excellent customer service, knowledgeable support, and secure packaging to ensure the safe delivery of your order. Prioritize quality and reliability by choosing a trusted peptide company for your SS-31 peptide needs.

Remember to conduct thorough research on peptide companies, read customer reviews, and consider their reputation within the scientific and research community before making a purchase.

What Are SS-31 Side Effects?

Based on the available scientific literature, SS-31 peptide (Bendavia or MTP-131) has a favorable safety profile. It has been studied in preclinical and clinical trials, and no significant adverse effects have been reported thus far. However, it’s important to note that the research on SS-31 is still ongoing, and individual responses may vary.

Since SS-31 is designed to target mitochondria and exert its effects within cells, it is believed to have a specific mode of action and limited off-target effects. Thus, the mechanism of action may contribute to its potential safety.

That being said, as with any peptide or medication, there is always a possibility of individual sensitivity or rare side effects. It’s important to note SS-31 is a research peptide and available for study use only.[5]

Overall, while the current research suggests that SS-31 is well-tolerated, ongoing research and monitoring are necessary to further evaluate its safety profile and potential side effects.

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Why Study SS-31?

Studying SS-31, also known as Bendavia or MTP-131, can be beneficial for several reasons:

Mitochondrial Dysfunction

SS-31 research focuses on the mitochondria, which play a critical role in cellular energy production, metabolism, and overall cellular health. Investigating SS-31 can deepen our understanding of mitochondrial dysfunction, which is implicated in various diseases and conditions such as cardiovascular disorders, neurodegenerative diseases, and age-related decline.[6]

SS-31 Peptide Research Potential

SS-31 shows promise as a potential research agent. By targeting and protecting mitochondria, SS-31 may help mitigate oxidative stress, reduce inflammation, and enhance cellular function. Studying SS-31’s mechanisms and effects can lead to the development of novel treatments for conditions associated with mitochondrial dysfunction.

Cardioprotection

Research on SS-31 highlights its potential cardioprotective effects. Investigating this peptide can provide insights into its ability to protect the heart from damage during ischemic events and improve cardiac function. Understanding the underlying mechanisms can pave the way for innovative strategies in cardiovascular medicine.

Neuroprotection

SS-31’s neuroprotective potential is another area of interest. By targeting mitochondria within brain cells, SS-31 may help protect neurons from damage, potentially benefiting neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases. Exploring SS-31’s effects on neuronal health can contribute to advancements in neuroprotection and neuroregeneration.

Drug Development

Studying SS-31 can aid in the development of new research strategies and formulations. It can provide valuable insights into peptide-based treatments, mitochondrial-targeted delivery systems, and combination treatments. SS-31 research has the potential to influence the development of innovative cures for various diseases and conditions.[7]

By studying SS-31, researchers can expand our knowledge of mitochondrial function and dysfunction, explore potential applications, and contribute to the development of novel treatments. Understanding the mechanisms and benefits of SS-31 can lead to advancements in regenerative medicine, cardiology, neurology, and other fields, ultimately improving patient care and quality of life.

Unlock the remarkable potential of cellular rejuvenation and optimize your research with SS-31 – the game-changing peptide that could revolutionize your studies.

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REFERENCES:

[1] SS-31, a Mitochondria-Targeting Peptide, Ameliorates Kidney Disease

[2] Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice

[3] Mitochondrial protein interaction landscape of SS-31

[4] SS-31 Peptide Reverses the Mitochondrial Fragmentation Present in Fibroblasts From Patients With DCMA, a Mitochondrial Cardiomyopathy

[5]  SS-31 BENDAVIA

[6] The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes

[7] The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action

Disclaimer

We bring this information to you for general knowledge purposes about research products and their uses. The medical problems discussed are for information use only. The products available on this website are for education and research use only. They are not for human consumption or use on animals. We supply Peptide Sciences products for laboratory research and not for any diagnostic, therapeutic or in vivo use on animals or the human body. Every product we sell is manufactured according to the research industry guidelines. The post may contain affiliate links but at no extra cost to you the buyer. Plus, external links for further resources. See our disclaimer here. For more read about us and our privacy policy.