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The Research Behind Peptides For Skincare

 Peptides for SkincareNowadays, vanity is everything, and the desire to look younger is ever-increasing. Celebrities, especially older ones flaunt air-brushed, flawless complexions, making many of us yearn to look as good. So how do they do it? Many procedures can help with skin aging, such as Botox injections or surgical procedures, but they are expensive. Fortunately, leading cosmetic businesses are producing more affordable and accessible alternatives to surgery to reduce aging in the form of skincare products. You will undoubtedly have heard of retinol, vitamin C, hyaluronic acid and peptides for skin care.

These astounding ingredients are now found in face creams, gels, serums, lotions and oils to help increase collagen[1] and reduce fine lines and wrinkles. They are the future of skin rejuvenation. In this post we look at the research of the best peptides for skin.

What Are Peptides?

Peptides [2] are chains of amino acids and the building blocks that form protein in the body. They are in every human cell in the body and play crucial roles in healthy body functioning, frequently acting as messengers. Peptides make the body work well; without them, the body will not function. They have many uses, from hormones and energy sources to building blocks for enzymes.

These tiny proteins are responsible for the health of the skin structure, including appearance, tissue firmness and elasticity. Collagen plays a significant role in making tissues strong to stand stretching. It gives strength and support to the body, helping fibroblasts form in the dermis of the middle layer of skin and stimulating new cells to grow. Without the collagen in the skin, the nails would be brittle, hair would be dry, and skin would be wrinkled.

How Peptides Work Best For The Skin?

Peptides naturally exist in the body. They act as communicators informing cells to produce new ones. They help cells communicate with each other to help keep the body healthy and strong. However, they can decline from age thirty, including skin proteins such as collagen and elastin, causing the skin to become thin and dry and have less elasticity. Luckily, enhancing the production of these valuable peptides with artificial versions will improve elasticity, firmness, and skin moisture. 

There are different types of anti-aging peptides, and all have varying abilities. Generally speaking, using the correct peptide on the skin will trick the body into sending a message to make more elastin, collagen and keratin. In addition, most of the peptides for the skin are safe and tolerated well by all skin types[3]. 

Peptides for Skincare

How Peptides Work In Skincare Products

The peptides in skin[4] care products don’t always replace the lost ones from the body. However, the body sees the additional peptides as signals to heal. With this, the body begins to produce more collagen where needed most. Thus, if the skin is aging, the peptides will signal the skin to increase collagen production and even hyaluronic acid to plump up the skin and restore a healthy boundary. When you use face products containing peptides, it tricks the skin into thinking there is a problem, so it encourages the process of a collagen boost.

When Should Peptides Be Used In Skincare Routine?

Anti-aging peptides are the new cutting-edge of skincare; they are in everything from face creams, gels, oils, lotions and serums. Leading cosmetic brands all have beauty products specially formulated with peptide ingredients. They can help reduce signs of aging without intrusive surgery.

Peptides for skincare have been around for a long time, but their popularity is growing continuously. They provide numerous benefits to the skin and help reduce the signs of aging. 

Peptides preserve skin elasticity and slow down the process of wrinkles forming. Many topical skin care products are available in skin care with active substances, including peptides. 

What Peptides Are Best For The Skin?

Skincare peptides are not all the same and work differently on the skin. Not all skincare peptides work the same on the skin. Scientists pay attention to detail and separate substances to analyze their varying uses. Here we give you the list of peptides for the skincare products that combat aging and what they do:

Carrier Peptides

Carrier peptides,[5] as the name suggests, they deliver essential trace elements such as copper and magnesium to the skin. Recent years have seen copper as a vital ingredient for producing more collagen, thus tightening skin and increasing elasticity. Copper ion is essential for growth and is naturally found in the blood of animals and humans. In research, copper peptides are proven to stop the appearance of age spots from UVA damage by brightening them. It can also reduce lines and wrinkles and even promote hair growth. Copper peptides help increase collagen and allow the skin to hang on to the collagen it makes for longer. They also regenerate and soothe inflammation.

Enzyme-Inhibitor Peptides

The enzyme-inhibitor peptide[6] works differently on the skin by stopping the natural process of collagen decline. Or putting the brakes on, you could say! Enzyme inhibitor peptides slow collagen decline and work to smooth lines and wrinkles. It does this by stopping muscle contractions of expression lines. The process is performed by signaling peptides that send information to the skin to make more collagen, elastin, hyaluronic acid, and proteins. The most common research peptide that works in this way is Matrixyl (palmitoyl pentapeptide-3). Matrixyl is the best-known peptide in skincare, studies show it can saturate the skin with double the amount of collagen.

Signal Peptides

Signal peptides,[7] or palmitoyl pentapeptides, are the most popular peptides in skincare products. They deliver messages to various skin parts to encourage elastin, collagen and structure proteins to improve the skin’s appearance by making it more plumped up and firmer. The most common signal research peptide is Tripeptide-29 or collagen peptide. Tripeptide-29 is a research peptide also known as collagen peptide. In studies, results have discovered it to impact collagen activity positively. It increases the skin’s condition and helps reduce fine lines and wrinkles.

Neurotransmitter Peptides 

Neurotransmitter peptides[8] are in Botox injections and topical treatment Argireline. They both work to relax facial muscles and stop them from contracting, helping to reduce laughter lines and wrinkles. Neurotransmitter peptides block the chemical release that stimulates muscle contraction of expression lines, ultimately smoothing wrinkles. Actual studies found these particular peptides actually reduce wrinkles by 30%. The most used neurotransmitter is Acetyl hexapeptide-3 peptide. Acetyl Hexapeptide-3 is Argireline, a topical research peptide that, in studies, effectively decreases wrinkles and improves the skin structure.

Benefits of Peptides for Skincare

Peptides for SkincareTo summarize, peptides in skin products fall into three main groups: signal, carrier and nerve inhibitor signal peptides. These do the job of messaging, signaling and triggering the collagen biological reaction of increasing skin firmness.


Skincare benefits from these topical peptides include:

Reduces fine lines – by encouraging collagen production to plump the skin so it appears fuller and plumper. Peptides can restore collagen and maintain a youthful skin look to the skin.

Strengthens skin barrier – peptides intensify the skin cells and improve the outer part of the skin.
Seals in hydration – with age, skin loses collagen, and this causes moisture loss; thus, peptides boost collagen and increase hydration.

Helps produce collagen – collagen declines with age, and as each year passes, it declines, causing dehydration, discolor, dull complexion, wrinkles and loss of firmness. Peptides signal skin cells to produce more collagen to replenish the loss with age.

Anti-inflammatory – properties in peptides, including antioxidants, can calm and stop skin irritation.

Promote skin firmness – the skin tightens with peptides doing the cell signaling to make more collagen. The nerve-stopping peptides stop the lines and wrinkles from moving muscles like Botox works.

Smoother look – the increase in collagen evens the skin to make it appear fuller and smoother.
Repairs skin damage – carrier peptides have healing properties and can heal from the inside to the outer layer.

How Peptides For Skincare Work?

These range of anti-aging peptides all work in different ways. But, generally, the outcome is the same decreasing the aging factors of thinning skin, fine lines and wrinkles. Topical peptides[9] increase essential skin proteins to improve firmness, elasticity, and moisture resulting in a glowing, healthy complexion with reduced lines. Primarily peptides for skin care side effects are few and are well-tolerated.

Most Frequently Asked Top 4 Skincare Questions

1.Which is Better, Retinol or Peptide?

Retinal boost collagen production in the skin but can leave it dry, inflamed and sensitive to the sun. Peptides are more gentle and moisturizing, making them the better option for sensitive skin.

2. Which is Better Niacinamide or Peptide?

Niacinamide and peptides in skincare products both have different qualities and target various skin flaws. But they are both safe and work well together. These two ingredients visibly improve skin tone, helps tighten the skin, and reduce lines, wrinkles, and discoloration.

3. What is the Best Peptide Serum?

Serums or moisturizers contain peptides to give younger, smoother-looking skin. The job of the serum is to promote firmness and replenish skin to provide a more youthful complexion. Serums are big business and safe. How often you use serums depends on skin type, but typically they are well-tolerated for twice-daily use. One of the best-sellers is Drunk Elephant Protini Powerpeptide Resurfacing Serum.

4. What is the Best Peptide Cream for Sagging Skin?

The best peptide that can firm sagging skin is Acetyl Tetrapeptide-2.[10]The peptide encourages collagen and elastin growth in the skin to tighten skin, firm-up and strengthen it to give smoother, more youthful skin.

 peptides for skincareWhich Peptide Is Best For Anti-Aging?

In research, many cosmetic peptides show promising signs of reducing wrinkles, tightening skin, and increasing collagen production and elasticity. The best injectable peptides for anti-aging are Sermorelin and Ipamorelin. These both promote the release of natural growth-hormone-release to help control age-related problems.

Growth hormone declines with age and cause skin to become loose and wrinkle, and lose elasticity. Ipamorelin and Sermorelin both tighten the skin, reduce lines and wrinkles and improve overall skin appearance. But, in this developing research business, there are many research peptide that are effective in aging skin for example:

Top 8 Best-Selling Research Peptides For Anti-Aging For Study Only


Epitalon[11] is an anti-aging research peptide that has been around for a long time in the science laboratory and is a significant player in decreasing age-related issues. Studies know Epitalon can replicate DNA, form new cells while replenishing old ones, and increase longevity. It can stop the process of aging cells that causes early aging.


In research studies Decapeptide-12 can improve skin texture and skin tone including whitening the skin.[12] It is an oligopeptide and can reduce skin damage from UVS rays.

Rigin Palmitoyl Tetrapeptide-7

From studies Rigin Palmitoyl Tetrapeptide-7 is a research peptide that has anti-inflammatory and anti-aging benefits. Rigin is in the early stages of study but is effective in aging problems and can promote collagen and elastin synthesis, ultimately improving skin elasticity and firmness.


Lipopeptide is a research peptide with many possible uses, including anti-aging. In studies, it improves cell production naturally in collagen; with this benefit it provides smoother skin and a reduction of wrinkles.


SNAP-8 is a research peptide with anti-aging benefits and can reduce wrinkles, especially under the eyes and on the forehead. It works similarly to Botox [13] but is cheaper. SNAP-8 has already been used in tiny amounts in gels, lotions, serums and emulsions to remove deep wrinkles and lines.

Syn-Coll (Palmitoyl Tripeptide-5)

Syn-coll[14] is a research peptide that has benefits in producing more collagen to decrease wrinkles. It already can be found in tiny amounts in anti-aging cosmetics.


Syn-ake is a research peptide that shows promising results in anti-aging studies. The peptide protein fragment from the venom of the Malaysian Temple Viper. It works similarly to Botox. Animal studies show it relaxes the facial muscle to reduce fine lines and wrinkles.

Vialox Pentapeptide-3v

Vialox is a research peptide that originates from snake venom. It works like Botox by causing slight paralysis to facial muscles and reducing lines and wrinkles. From animal studies, it can also smooth skin when used twice daily.

peptides for skincareWhere To Buy Research Peptides For Skincare

Are you are in the research business and looking  for cosmetic peptides for research? We supply a vast selection of research chemicals made in the USA by leading manufacturer Peptide Sciences. The peptides are tested for safety and have a purity of at least 99%. Every research product is premium quality, additive and TFA-free.

We guarantee an excellent service from easy ordering, to choice of payments and fast shipping. For those searching for cosmetic research peptides to study see the peptide list here:

-Acetyl Hexapeptide-3 (Argireline)
-AHK (Tripeptide-3)
-AHK-Cu (Copper Peptide)
-GHK Basic 50mg (Tripeptide-1)
-GHK Basic 200mg (Tripeptide-1)
-GHK-Cu 200mg (Copper Peptide)
-GHK-Cu 500mg (Copper Peptide)
-GHK-Cu 1000mg (Copper Peptide)
-Lipopeptide (Biopeptide EL)
-Matrixyl (palmitoyl pentapeptide-3)
-Melanostatin DM
-Pal-GHK (Palmitoyl Tripeptide-1)
-Palmitoyl Dipeptide-6
-Pentapeptide-18 (Leuphasyl)
-Rigin (Palmitoyl Tetrapeptide-7)
-SNAP-8 200mg
-SNAP-8 500mg
-SNAP-8 1000mg
-Syn-Coll (Palmitoyl Tripeptide-5)
-Tripeptide-29 (Collagen peptide)
-Vialox (Pentapeptide-3V)

<<BUY Research Peptides For Skincare – Laboratory Use only. Not For Human Use.>>

How To Get Natural Peptides For Skin

Up to now, we have looked at the artificial group of peptides for anti-aging problems and using them on the skin to reduce aging. But in fact, you can obtain peptides by changing your diet. For increasing collagen production; one of the best ways to do this is to eat collagen-rich food or take high-quality collagen supplements. Some highly-concentrated collagen-rich foods are:
-Bone broth
-Beans and Lentils
-Citrus fruit
-Egg Whites
-Hemp Seeds
-Red and yellow vegetables

Peptide supplements come from animal or plant sources such as eggs, beef or fish. The most common forms of peptide supplements are collagen and creatine. These natural peptide supplements can be added to your favorite drink, such as tea/coffee or a smoothie. But it’s essential to follow the instructions carefully. For vegans, who want to boost collagen with a supplement, there are alternative options in the form of Chaga mushroom powder.




[1] The Nutrition Source

[2] What Are Peptides?

[3]Ganceviciene R[Author] Skin anti-aging strategies

[4] Picture of the Skin

[5] Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy

[6] Enzymes

[7] Signal Peptide

[8] Peptide Neurotransmitters

[9] Author Gorouhi F Role of topical peptides in preventing or treating aged skin

[10] Acetyl tetrapeptide-2

[11] Epitalon

[12] Open-label evaluation of the skin-brightening efficacy of a skin-brightening system using decapeptide-12

[13] Botox 

[14] SYN®-COLL



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