Buy SNAP-8 Peptide here today at the best prices online. USA Peptides is a leader in supplying the best research chemicals. We supply a vast selection of research amino acids, peptides and proteins for study and educational use. Our research products are made in the USA by leading research company Peptide Sciences. The products are safe, and free of additives. These research chemicals undergo strict testing to supply the purest research chemicals online. For those in the research and science community we supply SNAP- 8 peptide in 3 strengths, including:
What Causes Aging?
One of the most characteristic features of skin aging is the increase in wrinkles on the face. This is a natural phenomenon, and occurs over a passage of time. It is a result of biochemical, histological and physiological changes that are accentuated by environmental exposure of the skin. There are also other secondary factors that cause the appearance of wrinkles on the face, such as:
-the force of gravity
-constant repetition of movements due to contractions of the muscles of facial expression
-pressure on the skin (for example, when sleeping)
They usually appear after the age of 25.
Regardless of the physiological origin of the wrinkle, the molecular mechanism involved in skin aging is directly related to
-changes in the conformation of the collagen triple helix
-the degradation of elastin polypeptides
-disorder in the packaging of the skin
-lipid matrix of the skin
On the other hand, it has been established in recent publications that these conformational changes and distortions of the lipid matrix packaging can be significantly prevented by modulating muscle contraction.
In summary, there are a series of factors that generate the appearance of wrinkles, but one of the most relevant is the contraction of the facial muscles.
Muscle Contraction and SNARE Complex
Muscles contract by receiving neurotransmitters (acetylcholine) released by vesicles at neuromuscular synapses. The SNARE complex is essential for the release of neurotransmitters in this synapse (A. Ferrer Montiel et al, The Journal of Biological Chemistry, 1997, 272, 2634-2638). SNARE is a ternary complex formed by 3 proteins: VAMP, Syntaxin and SNAP-25 (SyNaptosomal Associated Protein). The complex behaves as a cellular hook that captures the carrier vesicles and fuses them with the cell membrane, allowing the release of neurotransmitters.
What is Acetyl Octapeptide?
SNAP-8 is an octapeptide. The use of these types of peptides in dermatology and cosmetics is growing simply because we want to look younger. These cosmetic peptides work as an intercellular communication tool. They can direct the functioning of the skin and modulate biological processes in the dermis and epidermis. Cosmetic peptides target specific techniques and regulate skin processes reducing over time without significant side effects. They work by transmitting information in the cell, using various signaling mechanisms.
Buy SNAP-8 Peptide for Research
SNAP-8 is a research peptide and is for study use only. It is showing good results in treating anti-aging problems such as wrinkles and firmer skin. The advantage of SNAP-8 is it will be the key ingredient in topical creams, gels and serums making them easier to apply. Thus, getting rid of wrinkles will be easier than ever in the future! No more surgery, or Botox injections. For those searching for SNAP-8 Peptide or other similar research products buy here now!
How to use SNAP-8 Peptide
SNAP-8 is an elongation of the famous Argireline® hexapeptide, recognized for its effect similar to Botox or botulinum toxin. However SNAP-8 is vastly superior (twice as effective). It is an analog of the N-terminal end of the SNAP-25 protein and therefore competes with it for a position with the SNARE complex, modulating its formation. When the SNARE complex is slightly destabilized, the vesicles cannot dock and release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of wrinkles.
In short, the SNAP-8 peptide mediates a complex protein that is necessary for muscle contraction.
SNAP-8 vs. BOTOX
Botox (or botulinum toxin) paralyzes muscle by selectively blocking the release of acetylcholine at the neuromuscular junction. This is achieved by irreversible destruction of the SNAP-25 protein, resulting in muscle paralysis.
SNAP-8 acts on the same protein complex as the toxin, but in a completely different way: by competing with one of the proteins of the SNARE complex, it simply destabilizes the process and relaxes the muscle.
In short, Botox irreversibly breaks down the protein complex linked to muscle contraction, while SNAP-8 simply destabilizes it.
Reduces the depth of expression wrinkles produced by the contraction of the muscles of facial expression, especially on the forehead and around the eyes.
Prevents skin aging.
A softer alternative to Botox, which acts on the same mechanism of wrinkle formation but in a completely different way, avoiding the “frozen face” effect.
Some studies have associated it with a reduction in redness (Journal of Cosmetic Dermatology).