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What Does Ghrelin Do?

Ghrelin Acetate is a research peptide that is also called Lenomorelin. Ghrelin acetate comes from the natural peptide hormone produced in the gastrointestinal tract. The primary role of the ghrelin hormone is to promote food intake. It is referred to as the hunger hormone. In addition to food intake, ghrelin acetate promotes GI motility, growth hormone release, and gastric acid secretion. Further research shows ghrelin acetate has a primary role in sleep and wake behavior, glucose metabolism, learning, memory, and taste. Ultimately, the focus on ghrelin is changing the psychological behavior in eating and food preferences. 

History – The Discovery of Ghrelin Acetate

A. T. Pitavast’s original paper in the Journal of Biological Chemistry, revealed the ability of ghrelin in causing increased food intake in rats. The same paper reports the ability of ghrelin to increase gastric acid secretion in rodents and in humans. These two discoveries are often regarded as the “birth of ghrelin” and are credited to Dr. Pitavast. In a later paper published in 1994, A. T. Pitavast showed ghrelin could stimulate growth hormone production in humans and suggested that ghrelin may play a role in promoting weight gain in rodents.

Ghrelin Acetate has been known to increase the food consumption, decrease the body fat, and regulate bone growth and metabolism. Ghrelin may work as a natural appetite stimulant. In humans, however, its physiological function still remains unknown.

Ghrelin is a hormone that stimulates hunger for the treatment of cancer patients and loss of appetite and weight.

Background Studies

Between 60% and 80% of cancer patients suffer from losing appetite and weight. Ultimately, this is associated with reducing life expectancy and quality of life. Ghrelin, a hormone that stimulates hunger. It is secreted by the stomach and other organs in the body. Studies reveal that ghrelin can treat loss of appetite and weight loss in cancer patients. However, the effectiveness and safety of ghrelin is not yet proven in such patients. In this review, we examine all the evidence on the efficacy and safety of ghrelin in improving appetite and body weight in people with cancer and loss of appetite and weight.

Characteristics of the studies

Three studies recruited 59 cancer patients (37 men and 22 women) aged between 54 and 78 years. Forty-seven cancer patients completed treatment. The studies differed in study design and included patients with various types of cancer. The studies also discussed dosage, injection route, frequency and duration of treatment. One study compared ghrelin with placebo, while two studies compared different doses of ghrelin (higher amount versus lower dose). Outcomes of interest for cancer patients with appetite and weight loss, such as improvement in food consumption and body weight, were not adequately reported.

Government agencies funded all three included studies. One study received an additional grant from a pharmaceutical company.

key findings

There is no evidence that ghrelin administration alone or in combination resulted in changes in body weight. No conclusion could be reached about its side effects. The limited amount of information means that no conclusions could be drawn.

Quality of the evidence

The quality of evidence from studies is graded on four levels: high, moderate, low, or very low. High-quality evidence means that experts are very confident in the results. Very low-quality evidence suggests that we are very uncertain about the results. The evidence in this review was of deficient quality.

Authors’ conclusions:

There is insufficient evidence to support or refute the use of ghrelin in patients with cancer-related cachexia. Adequate powered randomized controlled trials focusing on evaluating the safety and efficacy of ghrelin in patients with cancer-related cachexia are warranted.

Some Information Courtesy of https://www.cochrane.org/CD012229/SYMPT_ghrelin-hunger-hormone-management-cancer-patients-loss-appetite-and-weight-loss

 

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Buy Hexarelin Acetate For those in the Research & Science Community be sure you buy Hexarelin Acetate here now! USA Peptides are one of the leading research chemicals stores online. With over 160 products you are sure to find what you are looking for. All of the research chemicals have undergone strict testing to guarantee at least 99% purity. This is important to ensure you get accurate results in this important work. After all, they are being studied by experts for future treatments and cures.

If this is your line of work and you want the best top-grade chemicals you have found the right place. For those who are new to this industry, all of the products on USA Peptides are for research and development purposes only. Here is a brief guide to the peptide Hexarelin Acetate.

Description of How Hexarelin Acetate Works

Hexarelin is a research peptide and also known as Hexarelin Acetate. It was created to increase muscle mass and strength, whilst burning fat. It is a synthetic peptide growth hormone secretagogue. Hexarelin stimulates the release of growth hormone, so it is used to treat conditions of growth failure. It produces higher levels of naturally produced growth hormone. It can be used by anyone with growth deficiency. But some of the known bodybuilders and athletes use it to improve their performance. But, we are not encouraging it for this use. From studies, Hexarelin benefits include:

  • Increases lean muscle and strength
  • An Increase in bone density
  • Helps reduce fat
  • Heals heart tissue and protects the heart
  • Slows down age-related changes that affect the condition of the skin and hair
  • Eliminates inflammatory process
  • Protects liver cells

What is Hexarelin?

Hexarelin is a (GH) growth hormone secretagogue peptide and is similar to GHRP-6. These peptides are part of the growth factor family and promote the release of growth hormones. It has the ability to treat growth hormone deficiency. The amino acid structure of Hexarelin is known as a hexapeptide and promotes growth hormone release. It can also work with the pituitary gland and the hypothalamus. So therefore out of the group of GHRP Hexarelin provides the highest growth hormone release.

A Brief Guide to Hexarelin Dosage

The peptide Hexarelin is classed as a GHRP (or growth hormone-releasing peptide) and is one of the strongest peptides in this group.  It has the capability to encourage growth hormone stimulation secretion. In studies, it can lower neonatal brain injuries in newborn babies. The type of dosage administered for effect is, 25mcg to 50mcg. It is used 1 – 4 times per day, and for the duration of 1 – 3 months. A gap of at least 3-4 hours is needed between doses, and the last one taken at night. This peptide is injected into the body fat of the abdominal area.

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